Early in the game you meet a librarian with her mouth sewn. Later, there’s an interesting sidequest related to her, where you need to hunt the witch that did that to her. There’s even a boss fight and a video sequence leading to this, which is not something I’d expect from a sidequest. Leaves an impression.
There are infested areas, where you encounter more monsters and supposed to find more loot. But the mechanics work in such a way that you usually waste more ammo that gain. So I just tend to keep away from those areas.
For half of the game we’re looking for that antropologist that would help us understand the visions. And a few minutes after we find her, she just… drowns. What a disappointment.